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Invitrogen
HOXA10 Polyclonal Antibody
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Product Details
PA5-140137
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HOXA10. Recombinant protein control fragment (Product #RP-109270).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: SQGDEEAHAS SSAAEELSPA PSESSKASPE KDSLGNSKGE NAANWLTAKS G
Highest antigen sequence indentity to the following orthologs: Mouse - 96%, Rat - 94%.
Target Information
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factorm HOXA10, that may regulate gene expression, morphogenesis, and differentiation. More specifically, HOXA10 may function in fertility, embryo viability, and regulation of hematopoietic lineage commitment. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the downstream homeobox A9 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: class I homeodomain; homeo box A10; homeobox protein; homeobox protein 1H; Homeobox protein Hox-1.8; Homeobox protein Hox-1H; Homeobox protein Hox-A10; homeobox protein HOXA10; Hox-18; PL; unnamed protein product
Gene Aliases: HOX1; HOX1.8; HOX1H; HOXA10; PL
UniProt ID: (Human) P31260
Entrez Gene ID: (Human) 3206
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
protein binding
histone deacetylase binding
sequence-specific double-stranded DNA binding
skeletal system development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
spermatogenesis
single fertilization
male gonad development
anterior/posterior pattern specification
proximal/distal pattern formation
regulation of gene expression
embryonic limb morphogenesis
prostate gland development
response to testosterone
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
uterus development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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