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Invitrogen
CDH10 Polyclonal Antibody
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Product Details
PA5-144705
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 250-394. Recombinant protein control fragment (Product #RP-109975).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SGTTTVNITL TDVNDNPPRF PQNTIHLRVL ESSPVGTAIG SVKATDADTG KNAEVEYRII DGDGTDMFDI VTEKDTQEGI ITVKKPLDYE SRRLYTLKVE AENTHVDPRF YYLGPFKDTT IVKISIEDVD EPPVFSRSSY LFEVH
Antigen sequence identity: Mouse 97%; Rat 97%
Target Information
CDH10 is a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is predominantly expressed in brain and is putatively involved in synaptic adhesions, axon outgrowth and guidance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Cadherin; cadherin 10 type 2; Cadherin-10; T2-cadherin
Gene Aliases: CDH10
UniProt ID: (Human) Q9Y6N8
Entrez Gene ID: (Human) 1008
cell morphogenesis
cell-cell junction assembly
cell adhesion
homophilic cell adhesion via plasma membrane adhesion molecules
calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
cell migration
adherens junction organization
cell-cell adhesion mediated by cadherin
cell-cell adhesion
synaptic membrane adhesion
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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