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Invitrogen
VGLUT3 Polyclonal Antibody
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Product Details
PA5-144781
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 4-71. Recombinant protein control fragment (Product #RP-110003).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KAFDTFKEKI LKPGKEGVKN AVGDSLGILQ RKIDGTTEEE DNIELNEEGR PVQTSRPSPP LCDCHCCG
Antigen sequence identity: Mouse 90%; Rat 84%
Target Information
Glucose is fundamental to the metabolism of mammalian cells. Several glucose transporter protein (Glut) isoforms have been identified and shown to function in response to insulin and IGF-1 induced signaling. GLUT-3 is detectable in a few normal cell type spermatids in testis with active spermatogenesis, placental trophoblast membranes, and neurons in brain. GLUT-3 staining is also detectable in human cancers including those of the ovary, lung, and testis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; solute carrier family 17 (vesicular glutamate transporter), member 8; Solute carrier family 17 member 8; unnamed protein product; Vesicular glutamate transporter 3; VGLUT 3; VGluT3
Gene Aliases: DFNA25; SLC17A8; VGLUT3
UniProt ID: (Human) Q8NDX2
Entrez Gene ID: (Human) 246213
neural retina development
ion transport
sodium ion transport
phosphate ion transport
chloride transport
neurotransmitter transport
sensory perception of sound
L-glutamate transport
ion transmembrane transport
synaptic transmission, glutamatergic
sodium ion transmembrane transport
sodium-dependent phosphate transport
regulation of synapse structure or activity
regulation of acetylcholine uptake
L-glutamate import
positive regulation of glutamate uptake involved in transmission of nerve impulse
phosphate ion homeostasis
transmembrane transport
cochlea development
neurotransmitter loading into synaptic vesicle
chloride transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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