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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SEVYPGQQYL QGGQYAPSTA QFAPSPGQPP APSPSYPGHR LPLQQGMTQS LSVPGPTGLH YKPTEQFNGQ
Antigen sequence identity: Mouse 86%; Rat 87%
ZIMP7, also known as ZMIZ2, is a novel PIAS (protein inhibitor of activated signal transducer and activator of transcription)-like protein and a transcriptional coactivator. ZIMP7 is expressed most abundantly in testis. The C-terminal proline-rich domain possesses a significant intrinsic transcriptional activity and this activity is inhibited by the N-terminus in the full-length ZIMP7. ZIMP7 and the related protein ZIMP10 interact with PIAS3 and enhances Androgen Receptor (AR)- mediated transcription. The interaction between ZIMP7 and SWI/SNF complex suggests a possible role for ZIMP7 in chromatin modification.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: PIAS-like protein Zimp7; Zinc finger MIZ domain-containing protein 2
Gene Aliases: HRIHFB2007; KIAA1886; ZIMP7; ZMIZ2
Entrez Gene ID: (Human) 83637
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