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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KEEQLPLRAG YQKTSDTIAP WFHGILTLKK ANELLLSTGM PGSFLIRVSE RIKGYALSYL SEDGCKHFLI DASADAYSFL GVDQLQHATL ADLVEYHKEE PITSLGKELL LYPCGQQ
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 93%.
SH2D4A inhibits estrogen-induced cell proliferation by competing with PLCG for binding to ESR1, blocking the effect of estrogen on PLCG and repressing estrogen-induced proliferation. SH2D4A may play a role in T-cell development and function.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ20967; protein phosphatase 1 regulatory subunit 38; protein SH(2)A; Shoca-2; unnamed protein product
Gene Aliases: 2210402M20Rik; PPP1R38; SH2A
UniProt ID: (Human) Q9H788, (Rat) Q6AYC8, (Mouse) Q9D7V1
Entrez Gene ID: (Human) 63898, (Rat) 306376, (Mouse) 72281
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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