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Invitrogen
TTLL12 Polyclonal Antibody
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Product Details
PA5-51810
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TTLL12. Recombinant protein control fragment (Product #RP-91500).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DYEKHFTVMN YDPDVVLKQV HCEEFIPEFE KQYPEFPWTD VQAEIFRAFT ELFQVACAKP PPLGLCDYPS SRAMYAVDLM LKWDNGPDGR RVMQPQILEV NFNPDCERAC RYHPTFFNDV FSTLFLDQPG
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 85%.
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Inactive tubulin--tyrosine ligase-like protein 12; tubulin tyrosine ligase-like family member 12; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12
Gene Aliases: dJ526I14.2; KIAA0153; TTLL12
UniProt ID: (Human) Q14166
Entrez Gene ID: (Human) 23170
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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