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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • NXF3 Antibodies

          Invitrogen

          NXF3 Polyclonal Antibody

          View all (7) NXF3 antibodies

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          Cite NXF3 Polyclonal Antibody

          • Antibody Testing Data (1)
          NXF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          NXF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          NXF3 Antibody (PA5-51832) in IHC (P)

          Immunohistochemical analysis of NXF3 in human testis using NXF3 Polyclonal Antibody (Product # PA5-51832) shows strong nuclear and cytoplasmic positivity in cells in seminiferous ducts, Leydig cells expressed moderate cytoplasmic staining. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NXF3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NXF3 Polyclonal Antibody

          Product Details

          PA5-51832

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human NXF3. Recombinant protein control fragment (Product #RP-92215).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2644917

          Product Specific Information

          Immunogen sequence: NPAGIPHFVH RELKSEKVEQ IKLAMNQQCD VSQEALDIQR LPFYPDMVNR DTKMASNPRK CMAASLDVHE ENIPTVMSAG EMDKWKGIEP GEKCADRSPV CTTFSDTSSN INSILELFPK LLCLDGQQSP RATLCGTEAH KRL

          Highest antigen sequence identity to the following orthologs: Mouse - 45%, Rat - 41%.

          Target Information

          This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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          Cite this product

          Bioinformatics

          Protein Aliases: Nuclear RNA export factor 3; TAP-like protein 3; TAPL-3

          View more View less

          Gene Aliases: NXF3; TAPL3

          View more View less

          UniProt ID: (Human) Q9H4D5

          View more View less

          Entrez Gene ID: (Human) 56000

          View more View less

          Function(s)
          nucleotide binding mRNA binding protein binding poly(A) RNA binding RNA metabolism protein
          Process(es)
          mRNA export from nucleus poly(A)+ mRNA export from nucleus
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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