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Invitrogen
KTN1 Polyclonal Antibody
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Product Details
PA5-51847
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human KTN1. Recombinant protein control fragment (Product #RP-89045).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ETLMVPSKRQ EALPLHQETK QESGSGKKKA SSKKQKTENV FVDEPLIHAT TYIPLMDNAD SSPVVDKREV IDLLKPDQVE GIQKSGTKKL KTETDKENAE VKFKDFLLSL KTMMFSEDEA LCVVDLLKEK SGVIQ
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 75%.
Target Information
Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CG-1 antigen; Kinectin; kinectin 1 (kinesin receptor); Kinesin receptor
Gene Aliases: CG1; KIAA0004; KNT; KTN1; MU-RMS-40.19
UniProt ID: (Human) Q86UP2
Entrez Gene ID: (Human) 3895
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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