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Invitrogen
OGFOD1 Polyclonal Antibody
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Product Details
PA5-51863
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human OGFOD1. Recombinant protein control fragment (Product #RP-96780).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EPENNQMAIS NNSQQSNEQT DPEPEENETK KESSVPMCQG ELRHWKTGHY TLIHDHSKAE FALDLILYCG CEGWEPEYGG FTSYIAKGED EELLTVNPES NSLALVYRDR ETLKFVKHIN HRSLEQKKTF PNRTGFWDFS F
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 81%.
Target Information
OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2-oxoglutarate and iron-dependent oxygenase domain containing 1; 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1; Prolyl 3-hydroxylase OGFOD1; Termination and polyadenylation 1 homolog; TPA1, termination and polyadenylation 1, homolog; uS12 prolyl 3-hydroxylase
Gene Aliases: 4930415J21Rik; AA387199; AA939912; AW061076; KIAA1612; mKIAA1612; OGFOD1; RGD1308848; TPA1
UniProt ID: (Human) Q8N543, (Mouse) Q3U0K8
Entrez Gene ID: (Human) 55239, (Mouse) 270086, (Rat) 307657
iron ion binding
L-ascorbic acid binding
peptidyl-proline dioxygenase activity
peptidyl-proline 3-dioxygenase activity
sulfonate dioxygenase activity
oxidoreductase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity
procollagen-proline dioxygenase activity
hypophosphite dioxygenase activity
DNA-N1-methyladenine dioxygenase activity
metal ion binding
dioxygenase activity
C-19 gibberellin 2-beta-dioxygenase activity
C-20 gibberellin 2-beta-dioxygenase activity
chromatin/chromatin-binding, or -regulatory protein
histone modifying enzyme
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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