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Invitrogen
WIPF1 Polyclonal Antibody
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Product Details
PA5-51995
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human WIPF1. Recombinant protein control fragment (Product #RP-102120).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PPPPVSRNGS TSRALPATPQ LPSRSGVDSP RSGPRPPLPP DRPSAGAPPP PPPSTSIRNG FQDSPCEDEW ESRFYFHPIS DLPPPEPYVQ TTKSYPSKLA RNESRSGSNR RERGAP
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.
Target Information
This gene encodes a protein that plays an important role in the organization of the actin cytoskeleton. The encoded protein binds to a region of Wiskott-Aldrich syndrome protein that is frequently mutated in Wiskott-Aldrich syndrome, an X-linked recessive disorder. Impairment of the interaction between these two proteins may contribute to the disease. Two transcript variants encoding the same protein have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: MGC111041; Protein PRPL-2; testicular tissue protein Li 226; WAS/WASL interacting protein family, member 1; WAS/WASL-interacting protein family member 1; WASP-interacting protein; Wiskott-Aldrich syndrome protein interacting protein; Wiskott-Aldrich syndrome protein-interacting protein
Gene Aliases: PRPL-2; WAS2; WASPIP; WIP; WIPF1
UniProt ID: (Human) O43516
Entrez Gene ID: (Human) 7456
actin cortical patch assembly
protein complex assembly
endocytosis
actin polymerization or depolymerization
regulation of cell shape
actin filament-based movement
Fc-gamma receptor signaling pathway involved in phagocytosis
positive regulation of actin nucleation
actin cortical patch localization
response to other organism
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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