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Invitrogen
CCDC134 Polyclonal Antibody
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Product Details
PA5-52029
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CCDC134. Recombinant protein control fragment (Product #RP-91496).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LLALKNLAQL NDIHQQYKIL DVMLKGLFKV LEDSRTVLTA ADVLPDGPFP QDEKLKDAFS HVVENTAFFG DVVLRFPRIV HYYFDHNSNW NLLIRWGISF CNQTGVFNQG PHSPILSLMA QEL
Highest antigen sequence identity to the following orthologs: Mouse - 96%, Rat - 95%.
Target Information
The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 134; dJ821D11.3; unnamed protein product
Gene Aliases: CCDC134; OI22
UniProt ID: (Human) Q9H6E4
Entrez Gene ID: (Human) 79879
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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