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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: AIILVNCDDD LWGDHSLEVE AGLPPGWRKI HDAAGTYYWH VPSGSTQWQR PTWELGDAED PGTGTEGIWG LRPPKGRSFS SLESSLDRSN SLSWYGGESY IQSMEPGAKC FAVRSL
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
The protein encoded by this gene is a member of the APBB protein family. It is found in the cytoplasm and binds to the intracellular domain of the Alzheimer's disease beta-amyloid precursor protein (APP) as well as to other APP-like proteins. It is thought that the protein encoded by this gene may modulate the internalization of APP. Multiple transcript variants encoding several different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Amyloid-beta A4 precursor protein-binding family B member 3; Fe65L2; Protein Fe65-like 2
Gene Aliases: APBB3; FE65L2
Entrez Gene ID: (Human) 10307
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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