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Invitrogen
DIAPH2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-52173
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DIAPH2. Recombinant protein control fragment (Product #RP-92145).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GGSEEPGGGR SNKRSAGNRA ANEEETKNKP KLNIQIKTLA DDVRDRITSF RKSTVKKEKP LIQHPIDSQV AMSEFPAAQP LYDERSLNLS EKEVLDLFEK MMEDMNLNEE KKAPLRNKDF TTKREMVVQY ISAT
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 39%.
Target Information
The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: diaphanous homolog 2; diaphorase-2; FLJ11167; mDia3; Premature ovarian failure 2A; RP11-212B22.1; similar to diaphanous homology 2 (DIAP2); unnamed protein product
Gene Aliases: AABR07040412.1; DIA; DIA2; Dia3; Diap2; DRF2; E430022I22Rik; POF; POF2; POF2A; RGD1564399
UniProt ID: (Human) O60879, (Mouse) O70566
Entrez Gene ID: (Human) 1730, (Rat) 317189, (Mouse) 54004
protein localization
biological_process
axon midline choice point recognition
actin cytoskeleton organization
actin filament polymerization
ephrin receptor signaling pathway
negative regulation of neuron projection regeneration
multicellular organismal locomotion
neuron projection retraction
female gamete generation
negative regulation of cellular component organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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