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Invitrogen
TRAK1 Polyclonal Antibody
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Product Details
PA5-52219
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRAK1. Recombinant protein control fragment (Product #RP-88802).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ELEDKYAECM EMLHEAQEEL KNLRNKTMPN TTSRRYHSLG LFPMDSLAAE IEGTMRKELQ LEEAESPDIT HQKRVFETVR NINQVVKQRS LTPSPMNIPG SNQSSAMNSL LSSCVSTPRS SFYGSDIGNV VLDNKTNSII LET
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
Target Information
Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors. Involved in mitochondrial motility. When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes. TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 106 kDa O-GlcNAc transferase-interacting protein; milton homolog 1; O-linked N-acetylglucosamine transferase interacting protein 106; OGT(O-Glc-NAc transferase)-interacting protein 106 KDa; Protein Milton; Trafficking kinesin-binding protein 1; trafficking protein, kinesin binding 1
Gene Aliases: KIAA1042; MILT1; OIP106; TRAK1
UniProt ID: (Human) Q9UPV9
Entrez Gene ID: (Human) 22906
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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