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Invitrogen
LITAF Polyclonal Antibody
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Product Details
PA5-52367
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LITAF. Recombinant protein control fragment (Product #RP-89429).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: APPSYEETVA VNSYYPTPPA PMPGPTTGLV TGPDGKGMNP PSYYTQPAPI PNNNPITVQT VYVQHPITFL DRPIQMCCPS CNKMIVSQLS YNAGALTWLS CGSLCLLGCI AGCCFIPFCV DALQDVDHYC PNC
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.
Target Information
Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CMT1C; FLJ38636; lipopolysaccharide-induced TNF-alpha factor; Lipopolysaccharide-induced tumor necrosis factor-alpha factor; LPS-induced TNF-alpha factor; MGC116698; MGC116700; MGC116701; MGC125274; MGC125275; MGC125276; p53-induced gene 7 protein; PIG 7; Small integral membrane protein of lysosome/late endosome; small integral membrane protein of the late endosome; tumor protein p53 inducible protein 7
Gene Aliases: LITAF; PIG7; SIMPLE; TP53I7
UniProt ID: (Human) Q99732
Entrez Gene ID: (Human) 9516
regulation of cytokine production
regulation of macrophage cytokine production
response to lipopolysaccharide
positive regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of transcription from RNA polymerase II promoter
cellular response to lipopolysaccharide
negative regulation of NIK/NF-kappaB signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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