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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KPSENHPLHN SGLLSLDPVQ DKTPLYSQLL QAYKWSNKLQ YHAGLASGLL NQQSLKRSAN QMGVSAKRRP KAQPTTLVLP PQYVDDVISR IDR
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cofactor required for Sp1 transcriptional activation subunit 8; CRSP complex subunit 8; Mediator complex subunit 27; Mediator of RNA polymerase II transcription subunit 27; MGC11274; P37 TRAP/SMCC/PC2 subunit; Transcriptional coactivator CRSP34
Gene Aliases: CRSP34; CRSP8; MED27
Entrez Gene ID: (Human) 9442
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