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Invitrogen
CCAR1 Polyclonal Antibody
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Product Details
PA5-52473
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CCAR1. Recombinant protein control fragment (Product #RP-89830).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KDVEENVGLI VYNGAMVDVG SLLQKLEKSE KVRAEVEQKL QLLEEKTDED EKTILNLENS NKSLSGELRE VKKDLSQLQE NLKISENMNL QFENQMNKTI RNLSTVMDEI HTVLKKDNVK NED
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 94%.
Target Information
IFI-44 (interferon-induced protein 44), also known as p44 or MTAP44 (microtubule-associated protein 44), is a 444 amino acid protein that localizes to the cytoplasm and, upon induction by IFN-betas, aggregates to form microtubular structures. Human IFI-44 shares 97% sequence similarity with its chimp counterpart, suggesting a conserved role between species. The gene encoding IFI-44 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson's disease, Gaucher disease, schizophrenia and Usher syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: CARP-1; CARP1; Cell cycle and apoptosis regulatory protein 1; Cell division cycle and apoptosis regulator protein 1; Death inducer with SAP domain; MGC44628; OTTHUMP00000019709; RP11-437A18.1; unnamed protein product
Gene Aliases: 2610511G16Rik; 9430036H15Rik; CARP1; CCAR1; DIS; RGD1560358; uc.285+
UniProt ID: (Human) Q8IX12, (Mouse) Q8CH18
Entrez Gene ID: (Human) 55749, (Rat) 361849, (Mouse) 67500
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcription coactivator activity
transcription corepressor activity
RNA binding
protein binding
ubiquitin protein ligase activity
ligand-dependent nuclear receptor transcription coactivator activity
poly(A) RNA binding
chromatin/chromatin-binding, or -regulatory protein
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
apoptotic process
positive regulation of cell proliferation
protein ubiquitination
positive regulation of cell migration
positive regulation of apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
cell division
transcription, DNA-templated
cell cycle
regulation of nucleic acid-templated transcription
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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