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          • Primary Antibodies ›
          • HMG20A Antibodies

          Invitrogen

          HMG20A Polyclonal Antibody

          View all (21) HMG20A antibodies

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          Cite HMG20A Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (3)
          HMG20A Antibody in Immunocytochemistry (ICC/IF)
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          HMG20A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          HMG20A Antibody (PA5-52515) in ICC/IF

          Immunofluorecent analysis of HMG20A in human cell line U-2 OS using HMG20A Polyclonal Antibody (Product # PA5-52515). Staining shows localization to nucleus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          HMG20A Antibody in Immunocytochemistry (ICC/IF)
          HMG20A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HMG20A Antibody in ChIP Assay (ChIP)
          HMG20A Polyclonal Antibody

          Product Details

          PA5-52515

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -

          ChIP assay (ChIP)

          1-10 µg
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human HMG20A. Recombinant protein control fragment (Product #RP-102524).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Amount

          10 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642474

          Product Specific Information

          Immunogen sequence: ATTGLNHPEV PYSSGATSST NNPEFVEDLS QGQLLQSESS NAAEGNEQRH EDEQRSKRGG WSKGRKRKKP LRDSNAPKSP LTGYVRFMNE RREQLRAKRP EVPFPEITRM LGNEWSKLP

          Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

          Target Information

          Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ10739; High mobility group protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1; unnamed protein product

          View more View less

          Gene Aliases: HMG20A; HMGX1; HMGXB1

          View more View less

          UniProt ID: (Human) Q9NP66

          View more View less

          Entrez Gene ID: (Human) 10363

          View more View less

          Function(s)
          DNA binding protein binding identical protein binding
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter chromatin organization regulation of transcription, DNA-templated regulation of gene expression negative regulation of protein sumoylation negative regulation of neuron differentiation
          It has to be done as per old AB suggested Products section.

          Disclaimer

          Close

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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