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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • HMG20A Antibodies

          Invitrogen

          HMG20A Polyclonal Antibody

          View all (21) HMG20A antibodies

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          Cite HMG20A Polyclonal Antibody

          • Antibody Testing Data (3)
          HMG20A Antibody in Immunocytochemistry (ICC/IF)
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          HMG20A Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 3

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          HMG20A Antibody (PA5-52515) in ICC/IF

          Immunofluorecent analysis of HMG20A in human cell line U-2 OS using HMG20A Polyclonal Antibody (Product # PA5-52515). Staining shows localization to nucleus. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          HMG20A Antibody in Immunocytochemistry (ICC/IF)
          HMG20A Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          HMG20A Antibody in ChIP Assay (ChIP)
          HMG20A Polyclonal Antibody

          Product Details

          PA5-52515

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -

          ChIP assay (ChIP)

          1-10 µg
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human HMG20A. Recombinant protein control fragment (Product #RP-102524).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642474

          Product Specific Information

          Immunogen sequence: ATTGLNHPEV PYSSGATSST NNPEFVEDLS QGQLLQSESS NAAEGNEQRH EDEQRSKRGG WSKGRKRKKP LRDSNAPKSP LTGYVRFMNE RREQLRAKRP EVPFPEITRM LGNEWSKLP

          Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.

          Target Information

          Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: FLJ10739; High mobility group protein 20A; HMG box domain containing 1; HMG box-containing protein 20A; HMG domain-containing protein 1; HMG domain-containing protein HMGX1

          View more View less

          Gene Aliases: HMG20A; HMGX1; HMGXB1

          View more View less

          UniProt ID: (Human) Q9NP66

          View more View less

          Entrez Gene ID: (Human) 10363

          View more View less

          Function(s)
          DNA binding transcription factor activity, sequence-specific DNA binding protein binding protein heterodimerization activity
          Process(es)
          negative regulation of transcription from RNA polymerase II promoter chromatin organization transcription, DNA-templated regulation of transcription, DNA-templated chromatin modification covalent chromatin modification negative regulation of neuron differentiation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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