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Invitrogen
MCPH1 Polyclonal Antibody
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Product Details
PA5-52535
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MCPH1. Recombinant protein control fragment (Product #RP-89875).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AVGLKSTQNK GTTSKISNSS EGEAQSEHEP CFIVDCNMET STEEKENLPG GYSGSVKNRP TRHDVLDDSC DGFKDLIKPH EELKKSGRGK KPTRTLVMTS MPSEKQNVVI QVVDKLKGFS IAPDVCETTT HVLSGKPLRT LNVLLGI
Highest antigen sequence identity to the following orthologs: Mouse - 55%, Rat - 52%.
Target Information
This protein is implicated in chromosome condensation and DNA damage induced cellular responses, and may play a role in neurogenesis and regulation of the size of the cerebral cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BRCT-repeat inhibitor of TERT expression 1; BRIT 1; FLJ12847; Microcephalin; unnamed protein product
Gene Aliases: BRIT1; MCPH1; MCT
UniProt ID: (Human) Q8NEM0
Entrez Gene ID: (Human) 79648
negative regulation of transcription from RNA polymerase II promoter
establishment of mitotic spindle orientation
mitotic cell cycle
regulation of gene expression
cerebral cortex development
regulation of centrosome cycle
regulation of inflammatory response
bone development
regulation of chromosome condensation
protein localization to centrosome
neuronal stem cell population maintenance
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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