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Invitrogen
CCDC90B Polyclonal Antibody
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Product Details
PA5-52795
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CCDC90B. Recombinant protein control fragment (Product #RP-90270).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AHLDAIRKDM VILEKSEFAN LRAENEKMKI ELDQVKQQLM HETSRIRADN KLDINLERSR VTDMFTDQEK QLMETTTEFT KKDTQTKSII SETSNKIDAE IASLKTLMES NKLE
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
Target Information
CCDC90B (Coiled-Coil Domain-Containing 90B), also known as MCUR1 (Mitochondrial Calcium Uniporter Regulator 1), is a gene located on chromosome 16p13.3 that encodes a protein involved in mitochondrial function. MCUR1 is a critical component of the mitochondrial calcium uniporter complex, which plays a vital role in regulating mitochondrial calcium uptake. Calcium uptake by mitochondria is essential for cellular metabolism, energy production, and apoptosis. MCUR1 interacts with other components of the uniporter complex to modulate the entry of calcium into the mitochondrial matrix, thereby influencing mitochondrial bioenergetics and reactive oxygen species (ROS) generation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Coiled-coil domain-containing protein 90B, mitochondrial; unnamed protein product
Gene Aliases: CCDC90B; CUA003; MDS011; MDS025
UniProt ID: (Human) Q9GZT6
Entrez Gene ID: (Human) 60492
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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