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Invitrogen
HEG1 Polyclonal Antibody
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Product Details
PA5-52842
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human HEG1. Recombinant protein control fragment (Product #RP-90450).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NQEDFSTVSS KEGVMVQTSG KSHAASDAPE NLTLLAETAD ARGRSGSSSR TNFTILPVGY SLEIATALTS QSGNLASESL HLPSSSSEFD ERIAAFQTKS GTASEMGTER AMGLSEEWTV
Highest antigen sequence identity to the following orthologs: Mouse - 43%, Rat - 38%.
Target Information
Receptor component of the CCM signaling pathway which is a crucial regulator of heart and vessel formation and integrity May act through the stabilization of endothelial cell junctions. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: heart of glass; Protein HEG homolog 1; unnamed protein product
Gene Aliases: HEG; HEG1; KIAA1237; MST112; MSTP112
UniProt ID: (Human) Q9ULI3
Entrez Gene ID: (Human) 57493
vasculogenesis
in utero embryonic development
endothelial cell development
endothelial cell morphogenesis
vasculature development
lymph vessel development
lymph circulation
cardiac atrium morphogenesis
ventricular trabecula myocardium morphogenesis
ventricular septum development
heart development
post-embryonic development
lung development
negative regulation of Rho protein signal transduction
multicellular organism growth
cell-cell junction organization
venous blood vessel morphogenesis
regulation of body fluid levels
cardiac muscle tissue growth
pericardium development
regulation of macromolecule metabolic process
regulation of biological quality
positive regulation of fibroblast growth factor production
protein localization to cell junction
negative regulation of membrane permeability
negative regulation of Rho-dependent protein serine/threonine kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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