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Invitrogen
DPEP1 Polyclonal Antibody
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Product Details
PA5-52984
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human DPEP1. Recombinant protein control fragment (Product #RP-89644).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SLIGVEGGHS IDSSLGVLRA LYQLGMRYLT LTHSCNTPWA DNWLVDTGDS EPQSQGLSPF GQRVVKELNR LGVLIDLAHV SVATMKATLQ LSRAPVIFSH SSAYSVCASR RN
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 82%.
Target Information
The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta-lactamase; Dehydropeptidase-I; Dipeptidase 1; hRDP; Microsomal dipeptidase; Renal dipeptidase; testicular tissue protein Li 57
Gene Aliases: DPEP1; MBD1; MDP; RDP
UniProt ID: (Human) P16444
Entrez Gene ID: (Human) 1800
proteolysis
leukotriene metabolic process
glutathione metabolic process
xenobiotic metabolic process
apoptotic process
antibiotic metabolic process
negative regulation of cell migration
cellular response to drug
negative regulation of apoptotic process
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
homocysteine metabolic process
cellular response to calcium ion
cellular response to nitric oxide
cellular lactam catabolic process
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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