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          • Primary Antibodies ›
          • NANOS2 Antibodies

          Invitrogen

          NANOS2 Polyclonal Antibody

          View all (7) NANOS2 antibodies

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          Cite NANOS2 Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          NANOS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          NANOS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          NANOS2 Antibody (PA5-53131) in IHC (P)

          Immunohistochemical analysis of NANOS2 in human testis using NANOS2 Polyclonal Antibody (Product # PA5-53131) shows moderate nuclear and cytoplasmic positivity in Leydig cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          NANOS2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          NANOS2 Polyclonal Antibody

          Product Details

          PA5-53131

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human NANOS2. Recombinant protein control fragment (Product #RP-89533).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2644461

          Product Specific Information

          Immunogen sequence: MQLPPFDMWK DYFNLSQVVW ALIASRGQRL ETQEIEEPSP GPPLGQDQGL GAPGANGGLG TLCNFCKHNG ESRHVYSSHQ LKTPDGVVVC PILRHYVCPV CGATGDQAHT LKYCPLNGGQ QSLYRRSGRN SAGRRVKR

          Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 74%.

          Target Information

          NANOS2 is a gene that encodes for a protein found in the testes and ovaries. It is a member of the NANOS family of proteins and plays a crucial role in the regulation of germ cell development. NANOS2 is involved in the maintenance of germ cell pluripotency and the suppression of somatic cell differentiation. It is also involved in the regulation of meiosis and the formation of gametes. Mutations in the NANOS2 gene have been associated with various reproductive disorders, including infertility and testicular germ cell tumors. NANOS2 is a target of research in the fields of reproductive biology and genetics.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Nanos homolog 2; NOS-2

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          Gene Aliases: NANOS2; NOS2; ZC2HC12B

          View more View less

          UniProt ID: (Human) P60321

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          Entrez Gene ID: (Human) 339345

          View more View less

          Function(s)
          RNA binding mRNA binding protein binding enzyme activator activity zinc ion binding metal ion binding
          Process(es)
          mRNA catabolic process regulation of translation spermatogenesis negative regulation of translation cell differentiation germ-line stem cell population maintenance negative regulation of meiotic nuclear division oogenesis mRNA destabilization
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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