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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • FAM3B Antibodies

          Invitrogen

          FAM3B Polyclonal Antibody

          View all (13) FAM3B antibodies

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          Cite FAM3B Polyclonal Antibody

          • Antibody Testing Data (5)
          FAM3B Antibody in Immunohistochemistry (IHC)
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          FAM3B Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 5

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          FAM3B Antibody (PA5-53397) in IHC

          Immunohistochemical staining of FAM3B in human prostate using FAM3B Polyclonal Antibody (Product # PA5-53397) shows weak to moderate positivity in cytoplasm granular in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          FAM3B Antibody in Immunohistochemistry (IHC)
          FAM3B Antibody in Immunohistochemistry (IHC)
          FAM3B Antibody in Immunohistochemistry (IHC)
          FAM3B Antibody in Immunohistochemistry (IHC)
          FAM3B Antibody in Western Blot (WB)
          FAM3B Polyclonal Antibody

          Product Details

          PA5-53397

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human FAM3B. Recombinant protein control fragment (Product #RP-90535).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2641402

          Product Specific Information

          Immunogen sequence: TPCPSDTYAY RLLSGGGRSK YAKICFEDNL LMGEQLGNVA RGINIAIVNY VTGNVTATRC FDMYEGDNSG PMTKFIQSAA PKSLLFMVTY DDGSTRLNND AKNAIEALGS KEIRN

          Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 75%.

          Target Information

          FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11 or PANDER, is a 235 amino acid secreted protein that localizes to discrete vesicular and perinuclear structures. Expressed at high levels in pancreas and at lower levels in kidney, colon, testis, prostate and small intestine, FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit Insulin secretion from beta-cells, possibly playing a role in overall pancreatic activity. Human FAM3B shares 78% sequence identity with its mouse counterpart, suggesting a conserved role between species. Three isoforms of FAM3B, designated A, B and C, exist due to alternative splicing events.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: 21-Feb; Cytokine-like protein 2-21; D21M16SJHU19e; family with sequence similarity 3, member B; pancreatic derived factor; Pancreatic-derived factor; PANDER; Protein FAM3B

          View more View less

          Gene Aliases: 2-21; C21orf11; C21orf76; FAM3B; ORF9; PANDER; PRED44; UNQ320/PRO365

          View more View less

          UniProt ID: (Human) P58499

          View more View less

          Entrez Gene ID: (Human) 54097

          View more View less

          Function(s)
          cytokine activity antimicrobial response protein
          Process(es)
          apoptotic process insulin secretion
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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