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Invitrogen
LGI2 Polyclonal Antibody
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Product Details
PA5-53555
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human LGI2. Recombinant protein control fragment (Product #RP-90365).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DLTHLSLANN HIKALPRDVF SDLDSLIELD LRGNKFECDC KAKWLYLWLK MTNSTVSDVL CIGPPEYQEK KLNDVTSFDY ECTTTDFVVH QTLPYQSVSV DTFNSKNDVY VAIAQPSMEN CMVLEW
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.
Target Information
The leucine-rich, glioma inactivated gene 2 (LGI2) is a member of the LGI family in which LGI1 is the exemplar. The LGI family consists of four of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 has been identified as a candidate tumor suppressor gene for glioma and plays a role in autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Despite its high homology with LGI1 and similar pattern of expression, mutations in LGI2 have not been found to be associated with ADTLE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Leucine-rich glioma-inactivated protein 2; Leucine-rich repeat LGI family member 2; leucine-rich, glioma inactivated 2; LGI1-like protein 2; unnamed protein product
Gene Aliases: KIAA1916; LGI2; LGIL2
UniProt ID: (Human) Q8N0V4
Entrez Gene ID: (Human) 55203
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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