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Invitrogen
NUDT4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-53612
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NUDT4. Recombinant protein control fragment (Product #RP-91860).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KVLQCHKPVH AEYLEKLKLG CSPANGNSTV PSLPDNNALF VTAAQTSGLP SSVR
Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.
Target Information
Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A. The major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2; diphosphoinositol polyphosphate phosphohydolase type II; diphosphoinositol polyphosphate phosphohydrolase type 2; DIPP-2; DIPP2 alpha; DIPP2 beta; KIAA0487; nucleoside diphosphate-linked moiety X motif 4; nudix (nucleoside diphosphate linked moiety X)-type motif 4; nudix hydrolase; nudix motif 4; nudix-type motif 4; Nudt4; rDIPP2; rDIPP2b; unnamed protein product
Gene Aliases: 4933436C10Rik; DIPP-2; DIPP-2B; DIPP2; DIPP2alpha; DIPP2beta; DRCF-5; HDCMB47P
UniProt ID: (Human) A0A024RBG1, (Rat) Q99MY2, (Mouse) Q8R2U6
Entrez Gene ID: (Human) 11163, (Rat) 94267, (Mouse) 71207
endopolyphosphatase activity
protein binding
diphosphoinositol-polyphosphate diphosphatase activity
pyrophosphatase activity
hydrolase activity
snoRNA binding
bis(5'-adenosyl)-hexaphosphatase activity
bis(5'-adenosyl)-pentaphosphatase activity
inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
inositol-5-diphosphate-1,3,4,6-tetrakisphosphate diphosphatase activity
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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