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Invitrogen
SLC4A11 Polyclonal Antibody
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Product Details
PA5-53730
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SLC4A11. Recombinant protein control fragment (Product #RP-91073).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TNTENEATSG GCVLLHTSRK YLKLKNFKEE IRAHRDLDGF LAQASIVLNE TATSLDNVLR TMLRRFARDP DNNEPNCNLD LLMAMLFTDA GAPMRGKVHL L
Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 78%.
Target Information
This gene encodes a voltage-regulated, electrogenic sodium-coupled borate cotransporter that is essential for borate homeostasis, cell growth and cell proliferation. Mutations in this gene have been associated with a number of endothelial corneal dystrophies including recessive corneal endothelial dystrophy 2, corneal dystrophy and perceptive deafness, and Fuchs endothelial corneal dystrophy. Multiple transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: bicarbonate transporter related protein 1; CDPD; MGC126418; MGC126419; NaBC1; OTTHUMP00000030097; Sodium borate cotransporter 1; sodium-coupled borate cotransporter 1; Solute carrier family 4 member 11; solute carrier family 4, sodium bicarbonate transporter-like, member 11; solute carrier family 4, sodium borate transporter, member 11; unnamed protein product
Gene Aliases: BTR1; CDPD1; CHED; CHED2; dJ794I6.2; NABC1; SLC4A11
UniProt ID: (Human) Q8NBS3
Entrez Gene ID: (Human) 83959
sodium channel activity
water transmembrane transporter activity
inorganic anion exchanger activity
hydrogen ion transmembrane transporter activity
bicarbonate transmembrane transporter activity
hydrogen ion channel activity
symporter activity
antiporter activity
transmembrane transporter activity
borate transmembrane transporter activity
protein dimerization activity
ion transport
sodium ion transport
anion transport
water transport
bicarbonate transport
cellular cation homeostasis
cellular response to oxidative stress
borate transmembrane transport
sodium ion transmembrane transport
fluid transport
borate transport
ion homeostasis
regulation of mitochondrial membrane potential
transmembrane transport
cellular hypotonic response
hydrogen ion transmembrane transport
regulation of mesenchymal stem cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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