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Invitrogen
USP4 Polyclonal Antibody
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Product Details
PA5-53820
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human USP4. Recombinant protein control fragment (Product #RP-101870).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NMVVADVYNH RFHKIFQMDE GLNHIMPRDD IFVYEVCSTS VDGSECVTLP VYFRERKSRP SSTSSASALY GQPLLLSVPK HKLTLESLYQ AVCDRISRYV KQPLPDEFGS SPL
Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 83%.
Target Information
The protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: deubiquitinating enzyme; Deubiquitinating enzyme 4; ubiquitin carboxyl-terminal esterase 4; Ubiquitin carboxyl-terminal hydrolase 4; ubiquitin specific peptidase 4 (proto-oncogene); ubiquitin specific protease 4 (proto-oncogene); Ubiquitin thioesterase 4; ubiquitin thiolesterase 4; ubiquitin-specific processing protease 4; Ubiquitin-specific-processing protease 4; Ubiquitous nuclear protein homolog; unnamed protein product
Gene Aliases: UNP; UNPH; USP4
UniProt ID: (Human) Q13107
Entrez Gene ID: (Human) 7375
spliceosomal tri-snRNP complex assembly
cytoplasmic translation
proteolysis
cellular response to starvation
protein deubiquitination
negative regulation of protein ubiquitination
regulation of protein stability
cellular response to nutrient levels
protein localization to cell surface
TORC1 signaling
negative regulation of translational initiation
positive regulation of translational initiation
negative regulation of TORC1 signaling
positive regulation of TORC1 signaling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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