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          • Primary Antibodies ›
          • LIAS Antibodies

          Invitrogen

          LIAS Polyclonal Antibody

          View all (7) LIAS antibodies

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          Cite LIAS Polyclonal Antibody

          Additional Information:
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          • Antibody Testing Data (1)
          LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          LIAS Antibody (PA5-53916) in IHC (P)

          Immunohistochemical analysis of LIAS in human urinary bladder using LIAS Polyclonal Antibody (Product # PA5-53916) shows moderate positivity in urothelial cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          LIAS Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          LIAS Polyclonal Antibody

          Product Details

          PA5-53916

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human LIAS. Recombinant protein control fragment (Product #RP-92467).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Amount

          20 µg

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2643369

          Product Specific Information

          Immunogen sequence: SVKTARNPPP LDASEPYNTA KAIAEWGLDY VVLTSVDRDD MPDGGAEHIA KTVSYLKER

          Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.

          Target Information

          LIAS belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.The protein encoded by this gene belongs to the biotin and lipoic acid synthetases family. It localizes in mitochondrion and plays an important role in alpha-(+)-lipoic acid synthesis. It may also function in the sulfur insertion chemistry in lipoate biosynthesis. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: lip-syn; Lipoate synthase; Lipoic acid synthase; Lipoyl synthase, mitochondrial; LS; MGC23245; unnamed protein product

          View more View less

          Gene Aliases: HGCLAS; HUSSY-01; LAS; LIAS; LIP1; LS; PDHLD

          View more View less

          UniProt ID: (Human) O43766

          View more View less

          Entrez Gene ID: (Human) 11019

          View more View less

          Function(s)
          catalytic activity transferase activity sulfurtransferase activity lipoate synthase activity metal ion binding iron-sulfur cluster binding 4 iron, 4 sulfur cluster binding
          Process(es)
          neural tube closure inflammatory response response to oxidative stress lipoate biosynthetic process protein lipoylation response to lipopolysaccharide
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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