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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: IHLENLLARS YFDPREAYPD GSSKEKRRAA IAQALAGEVS VVPPSRLMAL LGQALKWQQH QGLLPPGMTI DLFRGKAAVK DVEEEK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
SMU1 (suppressor of Mec8 and Unc-52 homolog), also known as BWD (brain-enriched WD), is a member of the WD-repeat SMU1 family and contains one CTLH domain, one LisH domain and six WD-repeats. SMU1 is a homolog of the C. elegans protein Smu1, a ubiquitously expressed nuclear protein that is believed to play a role in alternative splicing events of Unc-52. In mammals, SMU1 is a component of the spliceosome and appears to exhibit a conserved function, affecting the splicing of the mammalian Unc-52 homolog, namely Perlecan. Mutations in the gene encoding SMU1 may affect the function of the spliceosome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Smu-1 suppressor of mec-8 and unc-52 protein homolog; WD40 repeat-containing protein SMU1
Gene Aliases: SMU1
Entrez Gene ID: (Human) 55234
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