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Invitrogen
Defensin 6 Polyclonal Antibody
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Product Details
PA5-53992
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Defensin 6. Recombinant protein control fragment (Product #RP-92482).
Conjugate
Form
Liquid
Concentration
0.10 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: PLQAEDDPLQ AKAYEADAQE QRGANDQDFA VSFAEDASSS LRALGSTRAF TCHCRRSCYS TEYSYGTCTV MGINHRFC
Highest antigen sequence identity to the following orthologs: Mouse - 35%, Rat - 35%.
Target Information
Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Defensin, alpha 6; defensin, alpha 6, Paneth cell-specific; Defensin-6
Gene Aliases: DEF6; DEFA6; HD-6
UniProt ID: (Human) Q01524
Entrez Gene ID: (Human) 1671
immune system process
defense response
antibacterial humoral response
killing of cells of other organism
defense response to bacterium
innate immune response
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
defense response to fungus
membrane disruption in other organism
antimicrobial humoral immune response mediated by antimicrobial peptide
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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