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Invitrogen
PSIP1 Polyclonal Antibody
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FIGURE: 1 / 8
PSIP1 Antibody (PA5-54060) in ICC/IF
Immunofluorescence analysis of PSIP1 was performed using SH-SY5Y cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 10 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with PSIP1 Rabbit Polyclonal Antibody (Product # PA5-54060) at 4 µg/mL in 0.1% BSA and incubated overnight at 4 degree and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dilution of 1:2000... View More
Product Details
PA5-54060
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PSIP1. Recombinant protein control fragment (Product #RP-92573).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KQVETEEAGV VTTATASVNL KVSPKRGRPA ATEVKIPKPR GRPKMVKQPC PSESDIITEE DKSKKKGQEE KQPKKQPKKD EEGQ
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 83%.
Target Information
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CLL-associated antigen KW-7; Dense fine speckles 70 kDa protein; DFS 70; Lens epithelium-derived growth factor; PC4 and SFRS1-interacting protein; transcriptional coactivator p52/p75; Transcriptional coactivator p75/p52
Gene Aliases: DFS70; LEDGF; p52; p75; PAIP; PSIP1; PSIP2
UniProt ID: (Human) O75475
Entrez Gene ID: (Human) 11168
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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