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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: QAGNEEMVQI DLPIKRYREY ELVTPVSTNL EGRYLSHTLS ASHKKRSARD VSSNPEQLFF NITAFGKDFH LRLKPNTQL
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 84%.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: a disintegrin and metalloproteinase; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAM; ADAM-TS 3; ADAM-TS3; ADAMs; ADAMTS-3; ADAMTS3; KIAA0366; metalloendopeptidases; PC II-NP; procollagen II amino propeptide-processing enzyme; procollagen II N-proteinase; unnamed protein product; zinc metalloendopeptidase
Gene Aliases: ADAMTS-4; HKLLS3
UniProt ID: (Human) O15072
Entrez Gene ID: (Human) 9508
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