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Invitrogen
SFRS15 Polyclonal Antibody
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Product Details
PA5-54429
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human SFRS15. Recombinant protein control fragment (Product #RP-91822).
Conjugate
Form
Liquid
Concentration
0.4 mg/mL
Amount
40 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DLEERNRRSS GHRDRERDSR DRESRREKEE ARGKEKPEVT DRAGGNKTVE PPISQVGNVD TASELEKGVS EAAVLKPSEE LPAEATSSVE PEKDSGSAA
Highest antigen sequence identity to the following orthologs: Mouse - 77%, Rat - 82%.
Target Information
The family of SR factors all contain one or more RNA recognition motifs (RRM) and an SR-rich domain. They are not only essential for constitutive splicing, but also regulate splicing in a concentration-dependent manner by influencing the selection of alternative splice sites. Splicing factor arginine/serine-rich 15 (SFRS15), also designated CTD-binding SR-like protein RA4, contains one RRM and one SR-rich domains. SFRS15 interacts with C-terminal repetitive domain (CTD) of Pol II and is believed to functionally and physically link transcription and pre-mRNA processing. Localized to the nucleus, SFRS15 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CTD-binding SR-like protein RA4; pre-mRNA splicing SR protein rA4; SFR15; splicing factor serine alanine 15; Splicing factor, arginine/serine-rich 15; SR-like CTD-associated factor 4; SR-related and CTD-associated factor 4
Gene Aliases: FZS; KIAA1172; SCAF4; SFRS15; SRA4
UniProt ID: (Human) O95104
Entrez Gene ID: (Human) 57466
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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