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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PDE1C Antibodies

          Invitrogen

          PDE1C Polyclonal Antibody

          View all (11) PDE1C antibodies

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          Cite PDE1C Polyclonal Antibody

          • Antibody Testing Data (1)
          PDE1C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          PDE1C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          FIGURE: 1 / 1

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          PDE1C Antibody (PA5-54497) in IHC (P)

          Immunohistochemical analysis of PDE1C in human cerebral cortex using PDE1C Polyclonal Antibody (Product # PA5-54497) shows strong cytoplasmic positivity in glial cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          PDE1C Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PDE1C Polyclonal Antibody

          Product Details

          PA5-54497

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human PDE1C. Recombinant protein control fragment (Product #RP-92764).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.2 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2645325

          Product Specific Information

          Immunogen sequence: QSQVGFIDFI VEPTFTVLTD MTEKIVSPLI DETSQTGGTG QRRSSLNSIS SSDAKRSGVK TSGSEGSAPI NNSVISVDYK SFKATWTE

          Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 97%.

          Target Information

          Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin -dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 ).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Cam-PDE 1C; Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; Hcam3; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C, calmodulin-dependent 70kDa

          View more View less

          Gene Aliases: cam-PDE 1C; hCam-3; Hcam3; PDE1C

          View more View less

          UniProt ID: (Human) Q14123

          View more View less

          Entrez Gene ID: (Human) 5137

          View more View less

          Function(s)
          calmodulin-dependent cyclic-nucleotide phosphodiesterase activity calmodulin binding metal ion binding phosphodiesterase
          Process(es)
          signal transduction
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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