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Invitrogen
CDK5RAP3 Polyclonal Antibody
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Product Details
PA5-54627
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CDK5RAP3. Recombinant protein control fragment (Product #RP-93196).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ITGENVRGEL LALVKDLPSQ LAEIGAAAQQ SLGEAIDVYQ ASVGFVCESP TEQVLPMLRF VQKRGNSTVY EWRTGTEPSV VERPHLEELP EQV
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.
Target Information
This gene encodes a protein that has been reported to function in signaling pathways governing transcriptional regulation and cell cycle progression. It may play a role in tumorigenesis and metastasis. A pseudogene of this gene is located on the long arm of chromosome 20. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CDK5 activator-binding protein C53; CDK5 activator-binding protein C53; CDK5 regulatory subunit associated protein IC53-2; CDK5 regulatory subunit-associated protein 3; IC53-2; ischemic heart CDK5 activator-binding protein C53; LXXLL/leucine-zipper-containing ARF-binding protein; LXXLL/leucine-zipper-containing ARFbinding protein; OK/SW-cl.114; Protein HSF-27; unnamed protein product
Gene Aliases: 1810007E24Rik; BC002318; C53; C81486; CDK5RAP3; HSF-27; IC53; LZAP; MST016; MSTP016; OK/SW-cl.114; PP1553
UniProt ID: (Human) Q96JB5, (Mouse) Q99LM2
Entrez Gene ID: (Human) 80279, (Rat) 80278, (Mouse) 80280
regulation of cyclin-dependent protein serine/threonine kinase activity
regulation of mitotic cell cycle
brain development
cell proliferation
positive regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
regulation of neuron differentiation
positive regulation of transcription from RNA polymerase II promoter
protein ufmylation
positive regulation of protein localization to nucleus
positive regulation of signal transduction by p53 class mediator
regulation of signal transduction involved in mitotic G2 DNA damage checkpoint
negative regulation of cellular protein catabolic process
positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
liver development
negative regulation of protein phosphorylation
mitotic G2 DNA damage checkpoint
blood circulation
regulation of phosphatase activity
apoptotic nuclear changes
endoplasmic reticulum unfolded protein response
ribosome disassembly
response to endoplasmic reticulum stress
negative regulation of protein catabolic process
negative regulation of MAP kinase activity
negative regulation of protein kinase activity by regulation of protein phosphorylation
mitotic G2/M transition checkpoint
definitive erythrocyte differentiation
negative regulation of protein serine/threonine kinase activity
rescue of stalled ribosome
positive regulation of reticulophagy
positive regulation of proteolysis involved in cellular protein catabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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