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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • PNPO Antibodies

          Invitrogen

          PNPO Polyclonal Antibody

          View all (9) PNPO antibodies

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          Cite PNPO Polyclonal Antibody

          • Antibody Testing Data (8)
          PNPO Antibody in Immunocytochemistry (ICC/IF)
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          PNPO Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 8

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          PNPO Antibody (PA5-54722) in ICC/IF

          Immunofluorecent analysis of PNPO in human cell line U-251 MG using PNPO Polyclonal Antibody (Product # PA5-54722). Staining shows localization to nucleoplasm and cytosol. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
          Published figure supplied by benchsci-logo
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          PNPO Antibody in Immunocytochemistry (ICC/IF)
          PNPO Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          PNPO Antibody in Immunohistochemistry (IHC)
          PNPO Antibody in Immunohistochemistry (IHC)
          PNPO Antibody in Immunohistochemistry (IHC)
          PNPO Antibody in Immunohistochemistry (IHC)
          PNPO Antibody in Immunohistochemistry (IHC)
          PNPO Antibody in Western Blot (WB)
          PNPO Polyclonal Antibody

          Product Details

          PA5-54722

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:50-1:200
          -

          Immunocytochemistry (ICC/IF)

          0.25-2 µg/mL
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human PNPO. Recombinant protein control fragment (Product #RP-93193).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2645725

          Product Specific Information

          Immunogen sequence: SSVIPDREYL RKKNEELEQL YQDQEVPKPK SWGGYVLYPQ VMEFWQGQTN RLHDRIVFRR GLPTGDSPLG PMTHRGEEDW LYERLAP

          Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 90%.

          Target Information

          The enzyme encoded by this gene catalyzes the terminal, rate-limiting step in the synthesis of pyridoxal 5'-phosphate, also known as vitamin B6. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

          Have you cited this product in a publication?
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          Cite this product

          Bioinformatics

          Protein Aliases: epididymis secretory protein Li 302; FLJ10535; pyridoxal 5'-phosphate synthase; Pyridoxamine-phosphate oxidase; pyridoxine 5'-phosphate oxidase; Pyridoxine-5'-phosphate oxidase

          View more View less

          Gene Aliases: HEL-S-302; PDXPO; PNPO

          View more View less

          UniProt ID: (Human) Q9NVS9

          View more View less

          Entrez Gene ID: (Human) 55163

          View more View less

          Function(s)
          pyridoxamine-phosphate oxidase activity FMN binding oxidase
          Process(es)
          positive regulation of defense response to virus by host pyridoxine biosynthetic process vitamin B6 metabolic process pyridoxal phosphate biosynthetic process oxidation-reduction process mitophagy in response to mitochondrial depolarization xenophagy
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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          We're here to help

          Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.

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