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Invitrogen
RBCK1 Polyclonal Antibody
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Product Details
PA5-55006
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RBCK1. Recombinant protein control fragment (Product #RP-102083).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SVEDAQMHTV TIWLTVRPDM TVASLKDMVF LDYGFPPVLQ QWVIGQRLAR DQETLHSHGV RQNGDSAYLY LLSARNTSLN PQELQRERQL RMLEDLGFKD LTLQPRGPLE PGPPKPGVPQ EPGRGQPDAV PEP
Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 88%.
Target Information
RBCK1 encodes a protein that is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: HBV-associated factor 4; Heme-oxidized IRP2 ubiquitin ligase 1; Hepatitis B virus X-associated protein 4; HOIL-1; RanBP-type and C3HC4-type zinc finger-containing protein 1; RBCC protein interacting with PKC1; RING finger protein 54; RING-type E3 ubiquitin transferase HOIL-1; ubiquitin conjugating enzyme 7 interacting protein 3; Ubiquitin-conjugating enzyme 7-interacting protein 3; unnamed protein product
Gene Aliases: C20orf18; HOIL-1; HOIL1; PBMEI; PGBM1; RBCK1; RBCK2; RNF54; UBCE7IP3; XAP3; XAP4; ZRANB4
UniProt ID: (Human) Q9BYM8
Entrez Gene ID: (Human) 10616
protein polyubiquitination
positive regulation of macromolecule metabolic process
protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
defense response to bacterium
positive regulation of apoptotic process
positive regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of transcription, DNA-templated
T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
negative regulation of necroptotic process
regulation of primary metabolic process
protein linear polyubiquitination
positive regulation of NIK/NF-kappaB signaling
positive regulation of extrinsic apoptotic signaling pathway
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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