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Invitrogen
TRBP1 Polyclonal Antibody
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Product Details
PA5-55130
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TRBP1. Recombinant protein control fragment (Product #RP-91765).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: MNELNSVSDL DRCHLYLMVL TELINLHLKV GWKRGNPIWR VISLLKNASI QHLQEMDSGQ EPTVGSQIQR VVSMAALAMV CEAIDQKPEL QLDSLHAG
Highest antigen sequence identity to the following orthologs: Mouse - 64%, Rat - 59%.
Target Information
The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1-a (EF-1-a), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: RP5-827C21.5; TAR (HIV) RNA-binding protein 1; TAR (HIV-1) RNA binding protein 1; TAR RNA loop binding protein; TAR RNA-binding protein 1; TAR RNA-binding protein of 185 kDa; tRNA (guanosine(18)-2'-O)-methyltransferase TARBP1; tRNA methyltransferase 3 homolog; TRP-185
Gene Aliases: TARBP1; TRM3; TRMT3; TRP-185; TRP185
UniProt ID: (Human) Q13395
Entrez Gene ID: (Human) 6894
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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