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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SCP2 Antibodies

          Invitrogen

          SCP2 Polyclonal Antibody

          View all (21) SCP2 antibodies

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          Cite SCP2 Polyclonal Antibody

          • Antibody Testing Data (1)
          SCP2 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          SCP2 Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SCP2 Antibody (PA5-55506) in IHC

          Immunohistochemical staining of SCP2 in human liver using a SCP2 Polyclonal Antibody (Product # PA5-55506) shows strong cytoplasmic positivity in hepatocytes. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SCP2 Antibody in Immunohistochemistry (IHC)
          SCP2 Polyclonal Antibody

          Product Details

          PA5-55506

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human SCP2. Recombinant protein control fragment (Product #RP-94061).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2647024

          Product Specific Information

          Immunogen sequence: ATGLAQCAEL CWQLRGEAGK RQVPGAKVAL QHNLGIGGAV VVTLYKMGFP EAASSFRTHQ IEAVPTSSAS DGFKANLVFK EIEKKLEEEG EQFVKKI

          Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.

          Target Information

          This gene encodes two proteins: sterol carrier protein X (SCPx) and sterol carrier protein 2 (SCP2), as a result of transcription initiation from 2 independently regulated promoters. The transcript initiated from the proximal promoter encodes the longer SCPx protein, and the transcript initiated from the distal promoter encodes the shorter SCP2 protein, with the 2 proteins sharing a common C-terminus. Evidence suggests that the SCPx protein is a peroxisome-associated thiolase that is involved in the oxidation of branched chain fatty acids, while the SCP2 protein is thought to be an intracellular lipid transfer protein. This gene is highly expressed in organs involved in lipid metabolism, and may play a role in Zellweger syndrome, in which cells are deficient in peroxisomes and have impaired bile acid synthesis. Alternative splicing of this gene produces multiple transcript variants, some encoding different isoforms.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Acetyl-CoA C-myristoyltransferase; Non-specific lipid-transfer protein; NSL-TP; Propanoyl-CoA C-acyltransferase; SCP-2; SCP-2/3-oxoacyl-CoA thiolase; SCP-2/thiolase; SCP-chi; SCP-X; SCPX; Sterol carrier protein 2; Sterol carrier protein X

          View more View less

          Gene Aliases: NLTP; NSL-TP; SCP-2; SCP-CHI; SCP-X; SCP2; SCPX

          View more View less

          UniProt ID: (Human) P22307

          View more View less

          Entrez Gene ID: (Human) 6342

          View more View less

          Function(s)
          fatty-acyl-CoA binding receptor binding protein binding sterol transporter activity cholesterol binding propanoyl-CoA C-acyltransferase activity long-chain fatty acyl-CoA binding propionyl-CoA C2-trimethyltridecanoyltransferase activity oleic acid binding acyltransferase transfer/carrier protein
          Process(es)
          bile acid biosynthetic process peroxisome organization sterol transport positive regulation of intracellular cholesterol transport fatty acid beta-oxidation using acyl-CoA oxidase alpha-linolenic acid metabolic process lipid hydroperoxide transport
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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