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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PTKQVMMENK LEVHKDKTLK EAVEMAYKMM DLEEVIPLDC CRLVKYDEFH DYLERSYEGE EDTPMGLLLG GVKSTYMFDL LLETRKPDQV FQSY
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 97%.
Ubiquitin-specific protease that specifically deubiquitinates monoubiquitinated DNA polymerase beta (POLB), stabilizing POLB thereby playing a role in base-excision repair (BER). Acts as a regulator of cell growth and genome integrity. May also indirectly regulate CDC25A expression at a transcriptional level. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: deubiquitinating enzyme 47; Trf (TATA binding protein-related factor)-proximal homolog; ubiquitin thioesterase 47; ubiquitin thiolesterase 47; ubiquitin-specific-processing protease 47; unnamed protein product
Gene Aliases: TRFP
UniProt ID: (Human) Q96K76
Entrez Gene ID: (Human) 55031
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