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Invitrogen
UFL1 Polyclonal Antibody
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Product Details
PA5-56500
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human UFL1. Recombinant protein control fragment (Product #RP-94599).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GLFSAITRPT AVNSLISKYG FQEQLLYSVL EELVNSGRLR GTVVGGRQDK AVFVPDIYSR TQSTWVDSFF RQNGYLEFDA LSRLGIPDAV S
Highest antigen sequence identity to the following orthologs: Mouse - 93%, Rat - 96%.
Target Information
UFL1 (UFM1 Specific Ligase 1) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and UFM1 transferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E3 UFM1-protein ligase 1; E3 UFM1-protein transferase 1; LZAP-binding protein; Multiple alpha-helix protein located at ER; Novel LZAP-binding protein; Regulator of C53/LZAP and DDRGK1; Regulator of CDK5RAP3 and DDRGK1; RP3-393D12.1; unnamed protein product
Gene Aliases: KIAA0776; MAXER; NLBP; RCAD; UFL1
UniProt ID: (Human) O94874
Entrez Gene ID: (Human) 23376
DNA damage checkpoint
double-strand break repair via homologous recombination
DNA double-strand break processing
osteoblast differentiation
negative regulation of T cell mediated immune response to tumor cell
positive regulation of T cell mediated immune response to tumor cell
DNA repair
cellular response to DNA damage stimulus
blood circulation
positive regulation of cell proliferation
regulation of gene expression
positive regulation of autophagy
erythrocyte differentiation
DNA damage response, signal transduction by p53 class mediator
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
negative regulation of protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
regulation of proteasomal ubiquitin-dependent protein catabolic process
ribosome disassembly
regulation of protein localization
regulation of intracellular estrogen receptor signaling pathway
response to endoplasmic reticulum stress
regulation of I-kappaB kinase/NF-kappaB signaling
proteasome-mediated ubiquitin-dependent protein catabolic process
NLRP3 inflammasome complex assembly
regulation of inflammatory response
protein stabilization
negative regulation of T cell activation
positive regulation of T cell activation
hematopoietic stem cell differentiation
positive regulation of glial cell proliferation
reticulophagy
protein ufmylation
rescue of stalled ribosome
antiviral innate immune response
positive regulation of reticulophagy
negative regulation of signal transduction by p53 class mediator
response to L-glutamate
positive regulation of proteolysis involved in cellular protein catabolic process
negative regulation of IRE1-mediated unfolded protein response
protein K69-linked ufmylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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