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Invitrogen
OSGEPL1 Polyclonal Antibody
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Product Details
PA5-56541
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human OSGEPL1. Recombinant protein control fragment (Product #RP-89224).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DETGNVLGEA IHSQTEVHLK TGGIVPPAAQ QLHRENIQRI VQEALSASGV SPSDLSAIAT TIKPGLALSL GVGLSFSLQL VGQLKKPFIP IHHMEAHALT IRLTNKVEFP FLVLLISGGH CLLALVQGVS D
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 93%.
Target Information
OSGEPL1, also known as Qri7, is a 414 amino acid protein that belongs to the KAE1/YgjD family and exists as 3 alternatively spliced isoforms. In tRNAs that have codons beginning with adenine, OSGEPL1 is required for the formation of a threonylcarbamoyl group on adenosine. The gene that encodes OSGEPL1 contains about 16,568 bases and maps to human chromosome 2q32.2. Consisting of 237 million bases, chromosome 2 encodes over 1,400 genes and makes up approximately 8% of the human genome. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alstrom syndrome, is due to mutations in the ALMS1 gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: N6-L-threonylcarbamoyladenine synthase; O-sialoglycoprotein endopeptidase like 1; O-sialoglycoprotein endopeptidase-like protein 1; OSGEP-like protein 1; OSGEPL1; probable O-sialoglycoprotein endopeptidase 2; probable tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1; putative sialoglycoprotease type 2; t(6)A synthase; t(6)A37 threonylcarbamoyladenosine biosynthesis protein OSGEPL1; tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; tRNA threonylcarbamoyladenosine biosynthesis protein OSGEPL1
Gene Aliases: GCP1; OSGEPL1; Qri7
UniProt ID: (Human) Q9H4B0
Entrez Gene ID: (Human) 64172
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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