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Invitrogen
RSPH4A Polyclonal Antibody
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Product Details
PA5-56668
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RSPH4A. Recombinant protein control fragment (Product #RP-94638).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: DVSYNNAKQK ELRFDVFQEE DSNSDYDLQQ PAPGGSEVAP SMLEITIQNA KAYLLKTSSN SGFNLYDHLS NMLTKI
Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 67%.
Target Information
This gene encodes a protein that appears to be a component the radial spoke head, as determined by homology to similar proteins in the biflagellate alga Chlamydomonas reinhardtii and other ciliates. Radial spokes, which are regularly spaced along cilia, sperm, and flagella axonemes, consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein. Mutations in this gene cause primary ciliary dyskinesia 1, a disease arising from dysmotility of motile cilia and sperm. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: radial spoke head 4 homolog A; Radial spoke head protein 4 homolog A; Radial spoke head-like protein 3; radial spokehead-like 3; unnamed protein product
Gene Aliases: CILD11; dJ412I7.1; RSHL3; RSPH4A; RSPH6B
UniProt ID: (Human) Q5TD94
Entrez Gene ID: (Human) 345895
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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