Immunofluorecent analysis of SNX9 in human cell line A-431 using SNX9 Polyclonal Antibody (Product # PA5-56734). Staining shows localization to plasma membrane and cytosol.

SNX9 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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SNX9 Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of SNX9 was observed specifically in SK-MEL-30 cells and in MCF-7 cells using anti-SNX9 Polyclonal Antibody (Product # PA5-56734) in western blot. The relative expression levels of SNX9 within each cell line is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image SNX9 Polyclonal Antibody

Product Details

PA5-56734

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

Immunohistochemistry (IHC)

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Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human SNX9. Recombinant protein control fragment (Product #RP-94818).

3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.4 mg/mL

40 µg

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

AB_2647734

Product Specific Information

Immunogen sequence: YQGPATGDDD DWDEDWDGPK SSSYFKDSES ADAGGAQRGN SRASSSSMKI PLNKFPGFAK PGTEQYLLAK QLAKPKEKIP IIVGDYGPMW

Highest antigen sequence identity to the following orthologs: Mouse - 88%, Rat - 62%.

Target Information

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: MST155; MSTP155; OTTHUMP00000040083; Protein SDP1; putative ATP/GTP binding protein; RP11-266C7.10; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; Sorting nexin-9; unnamed protein product; Wiskott-Aldrich syndrome protein (WASP) interactor protein

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Gene Aliases: 2700073N08Rik; SDP1; SH3PX1; SH3PXD3A; SNX9; WISP

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UniProt ID: (Human) Q9Y5X1, (Mouse) Q91VH2

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Entrez Gene ID: (Human) 51429, (Mouse) 66616, (Rat) 683687

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Function(s)

protein binding 1-phosphatidylinositol binding lipid binding ubiquitin protein ligase binding phosphatidylinositol binding identical protein binding protein homodimerization activity cadherin binding Arp2/3 complex binding scaffold/adaptor protein

Process(es)

mitotic cell cycle mitotic cytokinesis intracellular protein transport endocytosis receptor-mediated endocytosis positive regulation of catabolic process protein transport endosomal transport positive regulation of actin filament polymerization cleavage furrow formation positive regulation of GTPase activity positive regulation of protein kinase activity positive regulation of membrane protein ectodomain proteolysis cell division lipid tube assembly protein-containing complex assembly membrane tubulation regulation of synaptic vesicle endocytosis transport cell cycle mitotic nuclear division vesicle organization positive regulation of protein oligomerization

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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SNX9 Polyclonal Antibody

SNX9 Antibody (PA5-56734) in ICC/IF

Product Details

PA5-56734

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Amount

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

RRID

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

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