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Invitrogen
CLNS1A Polyclonal Antibody
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Product Details
PA5-56824
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CLNS1A. Recombinant protein control fragment (Product #RP-95781).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: EDSDDDVEPI TEFRFVPSDK SALEAMFTAM CECQALHPDP EDEDSDDYDG EEYDVEAHEQ GQ
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 95%.
Target Information
Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ARPC1A; chloride channel regulatory protein; Chloride channel, nucleotide sensitive 1A; chloride channel, nucleotide-sensitive, 1A; Chloride conductance regulatory protein ICln; Chloride ion current inducer protein; ClCI; I(Cln); Methylosome subunit pICln; Reticulocyte pICln; reticulocyte protein ICln; SOP2-like protein; SOP2L
Gene Aliases: CLCI; CLNS1A; CLNS1B; ICLN
UniProt ID: (Human) P54105
Entrez Gene ID: (Human) 1207
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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