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          • Primary Antibodies ›
          • ICMT Antibodies

          Invitrogen

          ICMT Polyclonal Antibody

          View all (9) ICMT antibodies

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          Cite ICMT Polyclonal Antibody

          • Antibody Testing Data (2)
          ICMT Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.
          ICMT Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 2

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          ICMT Antibody (PA5-56903) in IHC

          Immunohistochemical staining of ICMT in human cerebellum using an ICMT Polyclonal Antibody (Product # PA5-56903) shows moderate cytoplasmic positivity in Purkinje cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          ICMT Antibody in Immunohistochemistry (IHC)
          ICMT Antibody in Western Blot (WB)
          ICMT Polyclonal Antibody

          Product Details

          PA5-56903

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          0.04-0.4 µg/mL
          -

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:50
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human ICMT. Recombinant protein control fragment (Product #RP-102610).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.05 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2642618

          Product Specific Information

          Immunogen sequence: RKAAMFTAGS NFNHVVQNEK SDTHTLVTSG VYAWFRH

          Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 92%.

          Target Information

          This gene encodes the third of three enzymes that post translationally modify isoprenylated C-terminal cysteine residues in certain proteins and target those proteins to the cell membrane. This enzyme localizes to the endoplasmic reticulum. Alternative splicing may result in other transcript variants, but the biological validity of those transcripts has not been determined.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Isoprenylcysteine carboxylmethyltransferase; MGC39955; pcCMT; PPMT; Prenylated protein carboxyl methyltransferase; Prenylcysteine carboxyl methyltransferase; protein-S isoprenylcysteine O-methyltransferase; Protein-S-isoprenylcysteine O-methyltransferase

          View more View less

          Gene Aliases: HSTE14; ICMT; MST098; MSTP098; PCCMT; PCMT; PPMT

          View more View less

          UniProt ID: (Human) O60725

          View more View less

          Entrez Gene ID: (Human) 23463

          View more View less

          Function(s)
          protein C-terminal carboxyl O-methyltransferase activity protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity protein modifying enzyme
          Process(es)
          cellular protein modification process C-terminal protein methylation protein targeting to membrane post-translational protein modification S-adenosylhomocysteine metabolic process S-adenosylmethioninamine metabolic process
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

          Learn more
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