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Invitrogen
CTRL Polyclonal Antibody
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Product Details
PA5-56958
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human CTRL. Recombinant protein control fragment (Product #RP-95844).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: VTAAHCNVSP GRHFVVLGEY DRSSNAEPLQ VLSVSRAITH PSWNSTTMNN DVTLLK
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 84%.
Target Information
The CTRL gene encodes chymotrypsin-like protein, a serine protease involved in the digestion of proteins by cleaving peptide bonds. It belongs to the chymotrypsin family of enzymes that are predominantly expressed in the pancreas and play crucial roles in the breakdown of dietary proteins in the small intestine. CTRL functions by hydrolyzing specific peptide bonds, contributing to efficient protein digestion and nutrient absorption. This enzyme's activity is tightly regulated to prevent premature activation within the pancreas, which could lead to pancreatitis or other digestive disorders. The study of the CTRL gene is significant in understanding the mechanisms of digestive health and in diagnosing pancreatic disorders. Furthermore, CTRL's enzyme activity and its role in proteolytic pathways make it an important target for research in digestive enzyme supplementation therapies and treatment strategies for conditions involving impaired protein digestion.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: chymotrypsin-like; Chymotrypsin-like protease CTRL-1
Gene Aliases: CTRL; CTRL1
UniProt ID: (Human) P40313
Entrez Gene ID: (Human) 1506
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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