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Invitrogen
APLF Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-57002
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human APLF. Recombinant protein control fragment (Product #RP-96194).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: NKVKRTSCMY GANCYRKNPV HFQHFSHPGD SDYGGVQIVG QDETDDRPEC PYGPSCYRKN PQHKIEYRHN TLPVRNV
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 74%.
Target Information
C2ORF13 is a component of the cellular response to chromosomal DNA single- and double-strand breaks.[supplied by OMIM, Mar 2008].
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: aprataxin- and PNK-like factor; apurinic-apyrimidinic endonuclease APLF; PNK and APTX-like FHA domain-containing protein; PNK and APTX-like FHA protein; unnamed protein product; XRCC1-interacting protein 1; zinc finger, CX5CX6HX5H motif containing 1
Gene Aliases: APFL; C2orf13; PALF; Xip1; ZCCHH1
UniProt ID: (Human) Q8IW19
Entrez Gene ID: (Human) 200558
nucleotide binding
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
protein binding
3'-5' exonuclease activity
histone binding
protein binding involved in protein folding
poly-ADP-D-ribose binding
histone chaperone activity
ADP-D-ribose modification-dependent protein binding
single strand break repair
DNA repair
regulation of DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
protein folding
cellular response to DNA damage stimulus
embryo implantation
regulation of epithelial to mesenchymal transition
protein localization to chromatin
DNA repair-dependent chromatin remodeling
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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