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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: PGSPVNSHLP GSPKQNRSTS TQVVFWAGIL QAQMCVLDLE EELEKTEGLK AGLKCCLPTP PVDLPGDTGL HSSPPENEDS GEDSSEPEGE GQAWLREGTP DSSPQW
Highest antigen sequence identity to the following orthologs: Mouse - 67%, Rat - 67%.
Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6 B; Exchange factor for ARF6 B; PH and SEC7 domain-containing protein 4; Pleckstrin homology and SEC7 domain-containing protein 4; Telomeric of interleukin-1 cluster protein
Gene Aliases: EFA6B; PSD4; TIC
Entrez Gene ID: (Human) 23550
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